Lab Members

Marie Zelená, M.Sc.
PhD student

Maruška completed her master’s studies in the field of parasitology at Charles University in  2020. During her undergraduate years, she worked in the laboratory of doc. Vladimír Hampl, where she focused on the assembly of iron-sulfur clusters in Monocercomonoides exilis, a unique eukaryotic organism with no mitochondria. As a parasitologist, she is naturally curious about the cell biology and biochemistry of various protists, and she got intrigued by the versatility of Trypanosoma brucei as a model organism. Therefore she decided to pursue a PhD in our lab, focusing on further characterization of distal-end localizing proteins of the trypanosome flagellum by advanced microscopy techniques.

Lucia Bubelínyová, B.Sc.
M.Sc. student

Lucia completed her Bachelor study at Masaryk University in Brno, where she worked in the Laboratory of Molecular Morphogenesis. Her project focused on the role of the primary cilia in the development of eyes. Lucia currently studies towards her Master degree at the Faculty of Science, Charles University, Prague. Being interested in the cilia she decided to join our lab and work on the composition of the distal tip of the primary cilium. 

Filip Šlapal, B.Sc.
M.Sc. student

Filip obtained his bachelor´s degree in 2020 in the Molecular Biology and Biochemistry of Organisms program of the Faculty of Natural Sciences, Charles University in Prague. In his bachelor’s thesis he focused on the role of the IFT machinery in the construction of the eukaryotic flagellum/cilium. Currently, he applies molecular and cell biology approaches to investigate mechanisms of the Intraflagellar transport particle movement along different regions of the primary cilia axoneme.

Peter Gorilák, M.Sc.
PhD student

Peter did his master studies in Genetics at Faculty of Natural Sciences, Comenius University in Bratislava, Slovakia. His master project was focused on DNA binding properties of yeast telomeric proteins, which was done in the laboratory of Prof. Ľubomír Tomáška.To widen his range of expertise Peter decided to change the research field. He joined our laboratory in September 2016. In his current dissertation project he study protein composition of mammalian cilia, particularly its distal end.

Martina Pružincová, B.Sc.
Master student

In 2015, Martina earned her Bachelor degree in Biology from Comenius University in Bratislava. During her undergraduate studies, she acquired additional experience by working in a laboratory at Polymer Institute SAS in Bratislava. She got especially interested in fluorescent microscopy and molecular cell biology. Therefore, she continued with her Master studies at Faculty of Science, Charles University in Prague. In 2016, she joined our laboratory, where she currently addresses questions regarding stability of protein complexes in the eukaryotic flagellum.

Luděk Štěpánek, Ph.D.
Postdoctoral fellow

After completing his undergraduate studies at Faculty of Science of Charles University in Prague, Luděk joined Dr. Gaia Pigino at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden to pursue his PhD studies. Here he encountered cilia and flagella for the first time, employing correlative light and electron microscopy to reveal how the intraflagellar transport is organized. After obtaining his doctorate, he worked under supervision of Prof. Stefan Diez from Technische Universität Dresden to study intraflagellar transport motors in vitro. Luděk joined our lab in July 2018 to study flagellum assembly using combination of imaging and biochemistry approaches.

Hana Váchová, M.Sc.
PhD student

Hanka started her scientific journey in the laboratory of Dr. Alena Panicucci Zíková in České Budějovice. She tried to answer the question what is the function of a newly discovered additional subunit in a highly evolutionary conserved F1 part of complex V in the mitochondrial respiratory chain. With this project she got passionate about the unique model organism Trypanosoma brucei. Therefore, she decided to continue in our lab to work on the tip of the trypanosome flagellum employing microscopy and biochemistry techniques.

Vladimír Varga, Ph.D.
Group leader

You can find more information on this page

Alumni

  • Glenda Paola Alquicer Barrera
  • Miroslava Šedinová
  • Radka Hrudíková
  • Zuzana Vaitová